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1

MMPI-2 Correlates of Sadomasochism in a Sexual Addiction Sample: Contrasting and Men and Women

Hopkins, Tiffany A., Brawner, Corey A., Meyer, Monica, Zawilinski, Laci, Carnes, Patrick J., Green, Bradley A.

Journal:

Sexual Addiction & Compulsivity

Year:

2016

Language:

english

File:

PDF, 333 KB

english, 2016

2

Synthesis of 1,3-diarylsubstituted indazoles utilizing a Suzuki cross-coupling/deprotection/N-arylation sequence

James M. Salovich, Craig W. Lindsley, Corey R. Hopkins

Journal:

Tetrahedron Letters

Year:

2010

Language:

english

File:

PDF, 459 KB

english, 2010

3

The locked-in syndrome: posterior stroke in the ED

Goldberg, Corey, Topp, Stephen, Hopkins, Christopher

Journal:

The American Journal of Emergency Medicine

Year:

2013

Language:

english

File:

PDF, 138 KB

english, 2013

4

ACS Chemical Neuroscience Molecule Spotlight on Latuda (Lurasidone; SM-13,496)

Hopkins, Corey R.

Journal:

ACS Chemical Neuroscience

Year:

2011

Language:

english

File:

PDF, 741 KB

english, 2011

5

ACS Chemical Neuroscience Molecule Spotlight on Suvorexant

Hopkins, Corey R.

Journal:

ACS Chemical Neuroscience

Year:

2012

Language:

english

File:

PDF, 148 KB

english, 2012

6

Discovery and Characterization of ML398, a Potent and Selective Antagonist of the D 4 Receptor with in Vivo Activity

Berry, Cynthia B., Bubser, Michael, Jones, Carrie K., Hayes, John P., Wepy, James A., Locuson, Charles W., Daniels, J. Scott, Lindsley, Craig W., Hopkins, Corey R.

Journal:

ACS Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 451 KB

english, 2014

7

The Return of D4 Dopamine Receptor Antagonists in Drug Discovery

Lindsley, Craig W, Hopkins, Corey R.

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 973 KB

english, 2017

8

Discovery, synthesis and characterization of a series of 7-aryl-imidazo[1,2-a]pyridine-3-ylquinolines as activin-like kinase (ALK) inhibitors

Engers, Darren W., Bollinger, Sean R., Felts, Andrew S., Vadukoot, Anish K., Williams, Charles, Blobaum, Anna L., Lindsley, Craig W., Hong, Charles C., Hopkins, Corey R.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2020

File:

PDF, 512 KB

2020

9

ChemInform Abstract: Efficient Synthesis of 1,4-Dihydro-2H-isoquinoline-3,5,8-triones via Cyclobutene Ring Expansion.

Peter Wipf, Corey R. Hopkins

Journal:

Year:

2000

File:

PDF, 33 KB

2000

10

ChemInform Abstract: Enantioselective Synthesis of the AB-Ring System of the Antitumor Antibiotic Tetrazomine.

Peter Wipf, Corey R. Hopkins

Journal:

Year:

2001

File:

PDF, 29 KB

2001

11

Convenient Synthesis of 4-Amino-3,5-disubstituted Pyrazoles in One-Step from the Corresponding Diketo Oximes.

Tahir Majid, Corey R. Hopkins, Brian Pedgrift, Nicola Collar

Journal:

Year:

2004

File:

PDF, 114 KB

2004

12

Novel Pyrazinone Inhibitors of Mast Cell Tryptase: Synthesis and SAR Evaluation.

Corey R. Hopkins, et al. et al.

Journal:

Year:

2005

File:

PDF, 141 KB

2005

13

6-Substituted-5H-pyrrolo[2,3-b]pyrazines via Palladium-Catalyzed Heteroannulation from N-(3-Chloropyrazin-2-yl)-methanesulfonamide and Alkynes.

Corey R. Hopkins, Nicola Collar

Journal:

Year:

2005

File:

PDF, 26 KB

2005

14

An Improved Method for the Synthesis of 6-Substituted-5H-pyrrolo[2,3-b]pyrazines via Palladium-Catalyzed Heteroannulation Using Microwave Heating.

Corey R. Hopkins, Nicola Collar

Journal:

Year:

2005

File:

PDF, 22 KB

2005

15

Synthesis of 6,7-Disubstituted-5H-pyrrolo[2,3-b]pyrazines via Palladium-Catalyzed Heteroannulation.

Corey R. Hopkins, Nicola Collar

Journal:

Year:

2005

File:

PDF, 22 KB

2005

16

ChemInform Abstract: Synthesis and SAR of a Novel Positive Allosteric Modulator (PAM) of the Metabotropic Glutamate Receptor 4 (mGluR4).

Richard Williams, Kari A. Johnson, Patrick R. Gentry, Colleen M. Niswender, Charles D. Weaver, P. Jeffrey Conn, Craig W. Lindsley, Corey R. Hopkins

Journal:

Year:

2010

File:

PDF, 16 KB

2010

17

ChemInform Abstract: Chemical Lead Optimization of a Pan Gq mAChR M1, M3, M5 Positive Allosteric Modulator (PAM) Lead. Part 1. Development of the First Highly Selective M5 PAM (I).

Thomas M. Bridges, J. Phillip Kennedy, Hyekyung P. Cho, Micah L. Breininger, Patrick R. Gentry, Corey R. Hopkins, P. Jeffrey Conn, Craig W. Lindsley

Journal:

Year:

2010

File:

PDF, 19 KB

2010

18

ChemInform Abstract: Synthesis of 1,3-Diaryl-Substituted Indazoles Utilizing a Suzuki Cross-Coupling/Deprotection/N-Arylation Sequence.

James M. Salovich, Craig W. Lindsley, Corey R. Hopkins

Journal:

Year:

2010

File:

PDF, 35 KB

2010

19

ChemInform Abstract: Synthesis and SAR of Novel, 4-(Phenylsulfamoyl)phenylacetamide mGlu4 Positive Allosteric Modulators (PAMs) Identified by Functional High-Throughput Screening (HTS).

Darren W. Engers, Patrick R. Gentry, Richard Williams, Julie D. Bolinger, C. David Weaver, Usha N. Menon, P. Jeffrey Conn, Craig W. Lindsley, Colleen M. Niswender, Corey R. Hopkins

Journal:

Year:

2011

File:

PDF, 23 KB

2011

20

ChemInform Abstract: Biomimetic Synthesis of Lignans

Craig W. Lindsley, Corey R. Hopkins, Gary A. Sulikowski

Journal:

Year:

2011

File:

PDF, 18 KB

2011

21

Novel pyrazinone inhibitors of mast cell tryptase: synthesis and SAR evaluation

Corey Hopkins, Kent Neuenschwander, Anthony Scotese, Sharon Jackson, Thaddeus Nieduzak, Henry Pauls, Guyan Liang, Keith Sides, Dona Cramer, Jennifer Cairns, Sebastien Maignan, Magali Mathieu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 358 KB

english, 2004

22

Design, synthesis, and biological activity of potent and selective inhibitors of mast cell tryptase

Corey R. Hopkins, Mark Czekaj, Steven S. Kaye, Zhongli Gao, James Pribish, Henry Pauls, Guyan Liang, Keith Sides, Dona Cramer, Jennifer Cairns, Yongyi Luo, Heng-Keang Lim, Roy Vaz, Sam Rebello, Sebast

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 310 KB

english, 2005

23

Development of N-4,6-pyrimidine-N-alkyl-N′-phenyl ureas as orally active inhibitors of lymphocyte specific tyrosine kinase

Jennifer A. Maier, Todd A. Brugel, Mark Sabat, Adam Golebiowski, Matthew J. Laufersweiler, John C. VanRens, Corey R. Hopkins, Biswanath De, Lily C. Hsieh, Kimberly K. Brown, Vijayasurian Easwaran, Mic

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 138 KB

english, 2006

24

Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-γ binding agents with potential application to the treatment of osteoporosis

Corey R. Hopkins, Steven V. O’Neil, Michael C. Laufersweiler, Yili Wang, Matthew Pokross, Marlene Mekel, Artem Evdokimov, Richard Walter, Maria Kontoyianni, Maria E. Petrey, Georgios Sabatakos, Jeff T

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 213 KB

english, 2006

25

Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part I: Development of the first highly selective M5 PAM

Thomas M. Bridges, J. Phillip Kennedy, Hyekyung P. Cho, Micah L. Breininger, Patrick R. Gentry, Corey R. Hopkins, P. Jeffrey Conn, Craig W. Lindsley

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 579 KB

english, 2010

26

Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)

Darren W. Engers, Patrick R. Gentry, Richard Williams, Julie D. Bolinger, C. David Weaver, Usha N. Menon, P. Jeffrey Conn, Craig W. Lindsley, Colleen M. Niswender, Corey R. Hopkins

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.16 MB

english, 2010

27

Heterobiaryl and heterobiaryl ether derived M5 positive allosteric modulators

Thomas M. Bridges, J. Phillip Kennedy, Corey R. Hopkins, P. Jeffrey Conn, Craig W. Lindsley

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 777 KB

english, 2010

28

Convenient synthesis of 4-amino-3,5-disubstituted pyrazoles in one step from the corresponding diketo oximes

Tahir Majid, Corey R. Hopkins, Brian Pedgrift, Nicola Collar

Journal:

Tetrahedron Letters

Year:

2004

Language:

english

File:

PDF, 250 KB

english, 2004

29

6-Substituted-5H-pyrrolo[2,3-b]pyrazines via palladium-catalyzed heteroannulation from N-(3-chloropyrazin-2-yl)-methanesulfonamide and alkynes

Corey R. Hopkins, Nicola Collar

Journal:

Tetrahedron Letters

Year:

2004

Language:

english

File:

PDF, 271 KB

english, 2004

30

An improved method for the synthesis of 6-substituted-5H-pyrrolo[2,3-b]pyrazines via palladium-catalyzed heteroannulation using microwave heating

Corey R. Hopkins, Nicola Collar

Journal:

Tetrahedron Letters

Year:

2004

Language:

english

File:

PDF, 250 KB

english, 2004

31

Synthesis of 6,7-disubstituted-5H-pyrrolo[2,3-b]pyrazines via palladium-catalyzed heteroannulation

Corey R. Hopkins, Nicola Collar

Journal:

Tetrahedron Letters

Year:

2005

Language:

english

File:

PDF, 119 KB

english, 2005

32

Separation of Cdc25 dual specificity phosphatase inhibition and DNA cleaving activities in a focused library of analogs of the antitumor antibiotic Dnacin

Peter Wipf, Corey R Hopkins, Eleanor O Phillips, John S Lazo

Journal:

Year:

2002

Language:

english

File:

PDF, 593 KB

english, 2002

33

Diisopropylsilyl ditriflate and di-tert-butysilyl ditriflate: new reagents for the protection of diols

E.J. Corey, Paul B. Hopkins

Journal:

Tetrahedron Letters

Year:

1982

Language:

english

File:

PDF, 203 KB

english, 1982

34

A mild procedure for the conversion of 1,2-diols to olefins

E.J. Corey, B. Hopkins

Journal:

Tetrahedron Letters

Year:

1982

Language:

english

File:

PDF, 238 KB

english, 1982

35

Proton magnetic resonance spectra of leukotriene a methyl ester (I), leukotriene B methyl ester diacetate (II) and 12-epi-6-E,8-Z-leukotriene B methyl ester diacetate (III; 5-S,12-di-HETE)

E.J. Corey, Paul B. Hopkins, Alan E. Barton, Ben Bangerter, Pierre Borgeat

Journal:

Year:

1982

Language:

english

File:

PDF, 283 KB

english, 1982

36

A Stereocontrolled and effective synthesis of leukotriene B (1).

E.J. Corey, Anthony Marfat, John Munroe, Kwan Soo Kim, Paul B. Hopkins, Francis Brion

Journal:

Tetrahedron Letters

Year:

1981

Language:

english

File:

PDF, 231 KB

english, 1981

37

Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: Unexpected ‘molecular switch’ from a closely related mGlu4 positive allosteric modulator

Thomas Utley, Dustin Haddenham, James M. Salovich, Rocio Zamorano, Paige N. Vinson, Craig W. Lindsley, Corey R. Hopkins, Colleen M. Niswender

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 2.52 MB

english, 2011

38

Solution-Phase Parallel Synthesis and SAR of Homopiperazinyl Analogs as Positive Allosteric Modulators of mGlu4

Cheung, Yiu-Yin, Zamorano, Rocio, Blobaum, Anna L., Weaver, C. David, Conn, P. Jeffrey, Lindsley, Craig W., Niswender, Colleen M., Hopkins, Corey R.

Journal:

ACS Combinatorial Science

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

39

ACS Chemical Neuroscience Molecule Spotlight on BMS-708163

Hopkins, Corey R.

Journal:

ACS Chemical Neuroscience

Year:

2012

Language:

english

File:

PDF, 141 KB

english, 2012

40

Allosteric Modulation of Seven Transmembrane Spanning Receptors: Theory, Practice, and Opportunities for Central Nervous System Drug Discovery

Melancon, Bruce J., Hopkins, Corey R., Wood, Michael R., Emmitte, Kyle A., Niswender, Colleen M., Christopoulos, Arthur, Conn, P. Jeffrey, Lindsley, Craig W.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 811 KB

english, 2012

41

“Molecular Switches” on mGluR Allosteric Ligands That Modulate Modes of Pharmacology

Wood, Michael R., Hopkins, Corey R., Brogan, John T., Conn, P. Jeffrey, Lindsley, Craig W.

Journal:

Year:

2011

Language:

english

File:

PDF, 917 KB

english, 2011

42

ACS Chemical Neuroscience Molecule Spotlight on Potiga (Ezogabine)

Hopkins, Corey R.

Journal:

ACS Chemical Neuroscience

Year:

2012

Language:

english

File:

PDF, 130 KB

english, 2012

43

Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4)

Richard Williams, Kari A. Johnson, Patrick R. Gentry, Colleen M. Niswender, Charles D. Weaver, P. Jeffrey Conn, Craig W. Lindsley, Corey R. Hopkins

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 878 KB

english, 2009

44

ChemInform Abstract: Discovery of N-(4-Methoxy-7-methylbenzo[d]thiazol-2-yl)isonicatinamide, ML293, as a Novel, Selective and Brain Penetrant Positive Allosteric Modulator of the Muscarinic 4 (M 4 ) Receptor.

Hopkins, Corey R., et al., et al.

Journal:

Year:

2012

File:

PDF, 21 KB

2012

45

Iterative experimental and virtual high-throughput screening identifies metabotropic glutamate receptor subtype 4 positive allosteric modulators

Ralf Mueller, Eric S. Dawson, Colleen M. Niswender, Mariusz Butkiewicz, Corey R. Hopkins, C. David Weaver, Craig W. Lindsley, P. Jeffrey Conn, Jens Meiler

Journal:

Journal of Molecular Modeling

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

46

Characterization of a Compound that Reduces Sensitivity to HERG Inhibitors and Prevents hERG-Related, Drug-Induced Arrhythmias in Isolated Rabbit Hearts

Potet, Franck, Lorinc, Amanda, Hopkins, Corey, Venkataraman, Raghav, Chaigne, Sebastien, Stepanovic, Svetlana, Lindsley, Craig, Baudenbacher, Franz, Kupershmidt, Sabina

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 38 KB

english, 2012

47

O143 Baseline characteristics of patients, with or without MRSA, in two double-blind, randomised, multinational, Phase 3 studies comparing telavancin with vancomycin for the treatment of complicated skin and skin structure infections

G.R. Corey, M.E. Stryjewski, V.G. Fowler Jr, A. Lentnek, A. Hopkins, M.M. Kitt, S.L. Barriere

Journal:

International Journal of Antimicrobial Agents

Year:

2007

Language:

english

File:

PDF, 48 KB

english, 2007

48

P844 The ATLAS studies:double-blind, randomised, active controlled, multinational Phase 3 trials comparing telavancin with vancomycin for the treatment of complicated skin and skin structure infections

G.R. Corey, M.E. Stryjewski, V.G. Fowler Jr, V. Skerk, A. Hopkins, M.M. Kitt, S.L. Barriere

Journal:

International Journal of Antimicrobial Agents

Year:

2007

Language:

english

File:

PDF, 76 KB

english, 2007

49

P845 ATLAS 1: the first Phase 3 study evaluating the new lipoglycopeptide, telavancin, for the treatment of patients with complicated skin and skin structure infections

G.R. Corey, M.E. Stryjewski, W.D. O'Riordan, V.G. Fowler Jr, D.P. Ross, A. Hopkins, M.M. Kitt, S.L. Barriere

Journal:

International Journal of Antimicrobial Agents

Year:

2007

Language:

english

File:

PDF, 86 KB

english, 2007

50

P846 ATLAS 2: a double-blind, randomised, active controlled, multinational Phase 3 study comparing telavancin with vancomycin for the treatment of patients with complicated skin and skin structure infections

G.R. Corey, M.E. Stryjewski, V.G. Fowler Jr, O. Teglia, A. Hopkins, M.M. Kitt, S.L. Barriere

Journal:

International Journal of Antimicrobial Agents

Year:

2007

Language:

english

File:

PDF, 79 KB

english, 2007